Gluten Sensitivity (Array 3)

Our knowledge of gluten illness – now officially termed ‘gluten-related disorders’ (GRDs) – has come an awfully long way in the past few years. We now know that gluten illness is a spectrum of disorders rather than all about coeliac disease.

You can have 4 main types:

  • Gluten Classical IgE Allergy – rare but does occur
  • Gluten Malabsorption – lack of enzymes to break it down, although I don’t think that occurs without a larger gluten problem personally; it’s a clue.
  • Coeliac Disease – the autoimmune attack on the villi in the gut and..
  • Non-Coeliac Gluten Sensitivity (NCGS) – every bit as serious as Coeliac Disease, an inflammatory and sometimes autoimmune attack anywhere in the body. People with an ‘intolerance’ ie. a delayed reaction to gluten would also come under this category. This is far more prevalent than coeliac disease.

Do you know the Most Common Signs of Gluten Intolerance or Gluten Sensitivity?

People typically shrug off the possibility of gluten sensitivity by saying, “I don’t have any digestive problems.” Little do they know that gluten produces digestive symptoms in only a minority of people (1 out of 8). For the majority of gluten damages the brain, the heart, the skin, the respiratory tract, or the joints. Even if your doctor has told you that you don’t have celiac disease, you CAN still be gluten sensitive.

Gluten Sensitivity Symptom Checklist

  • Weakened immune response and autoimmune disease
  • Brain fog
  • Depression and Anxiety
  • Skin conditions such as Eczema, Psoriasis, mouth sores, Canker sores, Dermatitis
  • Bloating, Constipation, Diarrhea, Gas
  • Hormonal Imbalances
  • Fatigue
  • Endocrine disorders (Thyroid, Adrenal, Sex Hormonal imbalances)
  • Migraines and Headaches
  • Joint pain
  • Vitamin and mineral deficiencies (Iron, Ferritin, Vitamin D, Zinc)

Stop Guessing, Get Tested

If you experience any of the above symptoms frequently, you may very well be intolerant to the foods you are eating. It is time to get it tested.

The Power of Knowing

The results from the Cyrex Array 3 panel can help determine which gluten subfractions may trigger unwanted inflammation. Then the personalized nutrition plan, based on your immune response, can assist with food choices that are better for your health and healing. When complying the Gluten Sensitivity Test results, many clinical symptoms associated with gluten sensitivity may be substantially improved or possible prevented altogether.

Research has proven that 50% of patients diagnosed with Celiac disease do not respond to the one protein being assessed in the conventional test. Instead they react to one or more of the other gluten proteins that are not measured in those conventional tests.
Additionally more labs are switching over to only offering deamidated gliadin because it is more sensitive for Celiac disease.

Unfortunately, the larger percentage of the population, Non-Celiac Gluten Sensitive patients, has been shown to be more reactive to native gliadin.

Cyrex Labs is the only lab that measures both native deamidated gliadin along with other gluten family proteins, the opioid peptides from both gluten and wheat, the lectin portion of wheat and wheat as a whole.

Because not every person’s gluten reactivity manifests as Celiac disease, Cyrex Labs measures antibodies to multiple transglutaminases to capture those patients whose gluten reactivity manifests as skin disorders or neurological complaints.

Antigens Testing

  • Wheat IgG
  • Wheat IgA
  • Wheat Germ Agglutinin IgG
  • Wheat Germ Agglutinin IgA
  • Native + Deamidated Alpha-Gliadin-33-mer IgG
  • Native + Deamidated Alpha-Gliadin-33-mer IgA
  • Alpha-Gliadin-17-mer IgG
  • Alpha-Gliadin-17-mer IgA * (Typically what gets tested)
  • Gamma-Gliadin-15-mer IgG
  • Gamma-Gliadin-15-mer IgA
  • Omega-Gliadin-17-mer IgG
  • Omega-Gliadin-17-mer IgA
  • Glutenin-21-mer IgG
  • Glutenin-21-mer IgA
  • Gluteomorphin+Prodynorphin IgG
  • Gluteomorphin+Prodynorphin IgA
  • Gliadin-Transglutaminase Complex IgG
  • Gliadin-Transglutaminase Complex IgA
  • Transglutaminase-2 IgG
  • Transglutaminase-2 IgA
  • Transglutaminase-3 IgG
  • Transglutaminase-3 IgA
  • Transglutaminase-6 IgG
  • Transglutaminase-6 IgA

Notice all the markers that don’t get checked on normal testing.

How It Works?

A small sample of your blood is sent to the laboratory overnight. Upon receiving the sample, the blood goes through a multi-step quality assurance process. After testing, the results are presented in a clear and easy to ready color-coded format.

Does Insurance Cover this test?
No.
Does Insurance Cover this test?
We have multiple options available depending on your geographic location.
How long will it take to receive my Test Results?
Web results are posted within 2-4 weeks. We will notify you as soon as we have test results
Is this a blood test?
Yes.
Is fasting required before taking the Test?
No.
What is the shipping procedure for the Test?
The lab that draws your blood will forward your blood specimen to laboratory.
Will Dr. Feldman discuss the test results with me?
Yes. Each test comes with a 30 minute post test review.
Is there a draw fee?
When using one of our contacted walk-in labs, there is no additional fee. Children will need to have a local hospital draw blood or local phlebotomist- A blood draw fee may be incurred.
What happens if I cancel my test?
Once tests have been ordered we are unable to offer a refund.

Coeliacs are not healing on the traditional gluten free diet

It is, in fact, well known that the vast majority of coeliacs do not heal their villi – and therefore continue to suffer the consequences of long-term malabsorption. Most ‘experts’ say it is because they must still be eating gluten. Whilst that may be so in some cases, there are simply too many with continued illness and symptoms for that always to be so. My view is that they are probably reacting to other types of grain gluten (or indeed other fractions of the food) or to known gluten-cross-reactive foods or gluten cross-contaminated foods (processed in the same facilities where other gluten products). And most aren’t even aware of that issue, let alone their doctors.